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为进一步了解营养性缺铁性贫血与细胞免疫功能的关系,本文测定了44名营养性缺铁性贫血(IDA)婴幼儿的T—淋巴细胞亚群的阳性细胞百分数,并选择了28名健康幼儿为对照组(C组).结果显示缺铁性贫血组(IDA)的CD_3~+％和CD_4~+％较正常对照组明显降低(P<0.01).且与血红蛋白的水平呈显著的正相关(r_1=0.6427,r_2=0.5974 P<0.005);CD_3~+％在正常对照组和缺铁性贫血组间无显著性差异(P<0.05),缺铁性贫血组的CD_4/CD_3比值较正常对照组明显降低,但与血红蛋白的水平无关.提示营养性缺铁贫血的细胞免疫功能低下与CD_3~+％和CD_4~+％降低有关,也是营养性缺铁性贫血易患各种感染性疾病的重要原因之一.
To further understand the relationship between nutritional iron deficiency anemia and cellular immune function, we measured the percentage of positive T-lymphocyte subsets in 44 infants with nutritional iron deficiency anemia (IDA) and selected 28 healthy The results showed that the levels of CD_3 ~ +% and CD_4 ~ +% in IDA group were significantly lower than those in control group (P <0.01), and the levels of hemoglobin and hemoglobin were significantly positive There was no significant difference between normal control group and iron deficiency anemia group (P <0.05). The ratio of CD_4 / CD_3 in iron deficiency anemia group was significantly higher than that in iron deficiency anemia group (r_1 = 0.6427, r_2 = 0.5974 P <0.005) The normal control group was significantly lower, but not with the hemoglobin level, suggesting that the nutritional deficiencies of cellular iron deficiency anemia and CD_3 ~ +% and CD_4 ~ +% reduction is also susceptible to nutritional iron deficiency anemia of various infectious One of the important causes of the disease.