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目的研究急性心肌梗死患者血清视黄醇结合蛋白4(RBP4)的变化及其意义。方法 59例急性心肌梗死患者,31例非急性心肌梗死患者,40例健康体检者,均采用酶联免疫吸附法(ELISA)测定血清RBP4水平。结果急性心肌梗死患者血清RBP4高于其他组(P<0.01),冠脉介入手术前后血清RBP4水平有明显变化(P<0.01)。结论 RBP4可作为急性心肌梗死早期诊断和疗效观察指标。
Objective To study the changes of serum retinol binding protein 4 (RBP4) in patients with acute myocardial infarction and its significance. Methods Serum RBP4 levels were measured by ELISA in 59 patients with acute myocardial infarction, 31 patients with non-acute myocardial infarction and 40 healthy subjects. Results Serum RBP4 in patients with acute myocardial infarction was significantly higher than that in other groups (P <0.01). Serum RBP4 levels were significantly changed before and after coronary intervention (P <0.01). Conclusion RBP4 can be used as early diagnosis and treatment of acute myocardial infarction indicators.