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目的观察住院患者输注红细胞的效果,分析影响红细胞输注效果的因素,为临床科学、合理输血提供依据。方法用回顾性分析的方法对本院2016年1月-3月486例红细胞输患者的临床病志、输血资料以及直接抗球蛋白试验的检验结果进行统计和分析。结果 486例住院患者共输注红细胞1 028次,其中无效输血有182次,输注无效率为17.7%,既往输血次数>3次、输血量>16 U红细胞输注无效率分别为42.7%与39.4%,比输血次数<3次、输血量<16 U红细胞输注无效率发生高;有妊娠史的患者红细胞输注无效的发生率为22.19%,比无妊娠史发生率高;恶性肿瘤患者与血液病患者红细胞输注无效的发生率分别为35.8%与25%,相比其他疾病发病率高;直接抗球蛋白试验阳性(31.6%)比阴性发生红细胞输注无效(14.1%)的几率增高。结论患者的疾病种类、既往输血次数、输血量、妊娠史及直接抗球蛋白试验的结果对输血效果的影响较为明显,临床医生应严格执行科学合理输血,尽量减少输血次数、重视直接抗球蛋白阳性结果,分析其阳性的原因,节约宝贵的血液资源。
Objective To observe the effect of transfusion of erythrocytes in hospitalized patients and analyze the factors influencing the transfusion of erythrocytes so as to provide basis for clinical science and rational blood transfusion. Methods A retrospective analysis of the hospital from January 2016 to March 486 cases of red blood cells in patients with clinical signs, blood transfusion data and direct antiglobulin test results were statistically analyzed. Results A total of 1 028 red blood cells were transfused in 486 inpatients, including 182 ineffective blood transfusions, 17.7% ineffective transfusion, previous transfusion> 3 times, and blood transfusion> 16 U, respectively. The inefficacy of erythrocyte infusion was 42.7% 39.4%, less than 3 times the number of blood transfusions, blood transfusions <16 U ineffective erythrocyte infusion occurred; the incidence of red cell infiltration in patients with pregnancy history was 22.19%, higher than the incidence of non-pregnancy; malignant tumor patients The incidence of ineffective erythrocyte infusion in patients with hematologic diseases was 35.8% and 25%, respectively, compared to other diseases; the incidence of direct antiglobulin test (31.6%) was less than that of negative erythrocyte infusion (14.1%) Increase. Conclusion The types of patients, the number of previous transfusions, the volume of blood transfusion, the history of pregnancy and the results of direct antiglobulin test have obvious effects on blood transfusion. Clinicians should strictly implement scientific and rational blood transfusion to minimize the number of transfusions and direct antiglobulin Positive results, analyze the reasons for its positive, save valuable blood resources.