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目的:探讨新疆维吾尔族胆囊结石病与血脂水平的关系。方法:回顾性分析我院2010年1月~2013年1月期间收集的80例新疆维吾尔族胆囊结石病患者(胆囊结石组)和120例新疆维吾尔族非胆囊结石病健康体检者(健康对照组)的临床资料。采用Olympus AU2700日本全自动生化仪器检测总胆固醇(TC)、甘油三脂(TG)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、载脂蛋白A(apoA)、载脂蛋白B(apoB)及肝功能指标。结果:①胆囊结石病组的TC、TG、LDL、ApoA和ApoB水平明显高于非胆囊结石病健康体检者对照组(P<0.05),HDL水平低于对照组,差异有统计学意义(P<0.05)。②胆囊结石病组女性患者的TC、TG和LDL高于男性,HDL水平低于男性,差异有统计学意义(P<0.05)。③胆囊结石病患者组总胆红素(TBIL)、间接胆红素(IBIL)、直接胆红素(DBIL)、天门冬氨酸氨基转移酶(AST)、碱性磷酸酶(ALP)、丙氨酸氨基转移酶(ALT)、谷氨酰转肽酶(GGT)、总蛋白(TP)、白蛋白(ALB)水平均较对照组无明显升高(P>0.05)。结论:新疆维吾尔族胆囊结石病的发生与血脂水平密切相关。
Objective: To investigate the relationship between Xinjiang Uygur gallstone disease and blood lipid levels. Methods: A retrospective analysis of 80 cases of gallstone disease patients (gallstone group) and 120 Xinjiang Uygur non-gallstone patients (healthy control group) collected in our hospital from January 2010 to January 2013 were retrospectively analyzed. ) Of the clinical data. (TC), triglyceride (TG), low density lipoprotein (LDL), high density lipoprotein (HDL), apolipoprotein A (apoA), apolipoprotein B (apoB) and liver function indicators. Results ① The levels of TC, TG, LDL, ApoA and ApoB in patients with gallstone disease were significantly higher than those in healthy controls (P <0.05), and the levels of HDL were lower than those in control group (P <0.05). ② The TC, TG and LDL of female patients with gallstone disease group were higher than those of male and the HDL level was lower than that of male, the difference was statistically significant (P <0.05). ③ The total bilirubin (TBIL), indirect bilirubin (IBIL), direct bilirubin (DBIL), aspartate aminotransferase (AST), alkaline phosphatase The levels of ALT, GGT, TP and ALB were not significantly higher than those of the control group (P> 0.05). Conclusion: The incidence of gallstone disease in Xinjiang Uighur is closely related to the level of blood lipid.