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目的探析食管癌患者术后胸内吻合口瘘的营养支持情况。方法选取医院收治的350例食管癌患者,32例术后出现胸内吻合口瘘,对其临床资料进行回顾性分析,根据不同的营养方式将其分为研究组(17例)和对照组(15例),研究组采取肠内、肠外联合生长抑制素治疗,对照组采取肠外营养支持治疗,比较2组病死率、胃肠减压量、瘘口愈合时间及胸腔闭式引流量等情况。结果研究组病死率为17.65%显著低于对照组的40.0%(P<0.01);研究组胃肠减压量(230.2±89.5)ml、瘘口愈合时间(20.3±8.4)d及胸腔闭式引流量(450.3±210.6)ml与对照组比较差异均有统计学意义(P<0.01)。结论给予食管癌术后胸内吻合口瘘患者肠内、肠外联合生长抑制素营养支持治疗,可明显改善患者的营养状态,预防并发症,促进患者康复。
Objective To investigate the nutritional support of intrathoracic anastomotic fistula in patients with esophageal cancer. Methods A total of 350 patients with esophageal cancer admitted to the hospital were enrolled in this study. Thirty-two cases of intrathoracic anastomotic fistula were retrospectively analyzed. According to different nutritional methods, they were divided into study group (17 cases) and control group 15 cases). The study group was treated with enteral and parenteral combined with somatostatin and the control group with parenteral nutrition support. The mortality, gastrointestinal decompression, fistula healing and thoracic closure drainage were compared Happening. Results The case fatality rate of the study group was 17.65%, which was significantly lower than that of the control group (40.0%, P <0.01). The gastrointestinal decompression volume (230.2 ± 89.5) ml, fistula healing time (20.3 ± 8.4) Drainage (450.3 ± 210.6) ml compared with the control group were statistically significant (P <0.01). Conclusions The administration of enteral and parenteral combined with somatostatin in patients with esophageal cancer after thoracic anastomotic leakage can significantly improve the nutritional status, prevent complications and promote the recovery of patients.