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许多研究表明辅助化疗对头颈部鳞癌有效。与其它化疗方案相比,争光霉素、环磷酰胺、氨甲喋呤、5-氟尿嘧啶(简称B-CMF)方案毒性低,药物效能大。作者进行了这组头颈部癌高危患者随机抽样研究。1979年7月至1982年9月共观察133例晚期头颈部鳞癌,经过筛选本试验选用83例,随机分为两组,化疗组43人(标准治疗前后接受化疗),对照组40人(仅作标准治疗)。标准治疗包括原发肿瘤和局部淋
Many studies have shown that adjuvant chemotherapy is effective for head and neck squamous cell carcinoma. Compared with other chemotherapy regimens, bleomycin, cyclophosphamide, methotrexate, and 5-fluorouracil (abbreviated as B-CMF) regimens have low toxicity and high drug efficacy. The authors conducted a random sample of high-risk patients with head and neck cancer. From July 1979 to September 1982, 133 cases of advanced head and neck squamous cell carcinoma were observed. After screening, 83 cases were selected and randomly divided into two groups. 43 patients in the chemotherapy group (standard chemotherapy before and after treatment) and 40 in the control group. (standard treatment only). Standard treatments include primary tumors and topical showers