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原发性人类疱疹病毒-6(HHV-6)感染引起幼儿急疹(猝发疹;exanthem subitum)可能发生中枢神经系并发症,提示在此病程中,病毒很可能侵入中枢神经系而引起脑炎或脑病。该文报道1例幼儿急疹在发病前期即出现脑炎,重点研究了此病病毒学和组织病理学的表现。病例九个月女婴,因高热和全身阵挛性惊厥人院。入院前一天下午体温突然升到39.2℃,清晨出现全身阵挛性惊厥,每次持续1分钟,四小时内共约10次。早晨呕吐几次同时伴有嗜睡和木僵。患儿营养佳,前囱正常。此患儿系足月正常娩出。入院复查体温38.6℃,CT和EEG均未见异常,脑脊液(CSF)检查蛋白和糖正常,CSF内也未见(淋巴)细胞增多(pleocy-tosis)。外周血内WBC 25×10~9/L,淋巴细胞19%,血液
Central nervous system complications may occur in children with acute herpes simplex virus (HHV-6) infection, suggesting that the virus may invade the central nervous system and cause encephalitis Or encephalopathy. This article reports a case of infant acute rash encephalitis in the early onset of the disease, focusing on the virological and histopathological manifestations of the disease. Case of nine-month-old baby girl, because of fever and general clonic convulsive hospital. On the day before admission, the temperature suddenly rose to 39.2 ° C in the afternoon and showed general clonic convulsions in the morning, lasting 1 minute each, for a total of about 10 times in four hours. Several morning vomit accompanied by lethargy and stupor. Children with good nutrition, normal before the chimney. This child was given normal term. Admitted to hospital for examination of body temperature 38.6 ℃, CT and EEG were no abnormalities, cerebrospinal fluid (CSF) check the protein and sugar normal, no CSF (lymphocytosis) cells (pleocytosis). WBC peripheral blood 25 × 10 ~ 9 / L, 19% of lymphocytes, blood