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动物体对结核感染的特异性免疫以细胞免疫为主,而胸腺在机体免疫功能方面占有重要地位。我们应用近交系小鼠观察了结核杆菌感染后对胸腺的影响,发现小鼠在感染结核杆菌H_(37)Rv3周时,胸腺缩小,细胞数下降。实验方法一、动物来源:中国科学院实验动物中心供应的JCR及C_(57)近交系小鼠,雄性,JCR系体重20克左右,C_(57)18克左右。二、分组:每组小鼠分别为8～28只。各设结核感染组及自然对照组,进行比较。三、菌株:标准人型结核杆菌(H_(37)RV),在改良罗氏培养基上次代培养2～3周,待生长丰盛,用生
The specific immunity of animals to TB infection is mainly cellular immunity, while the thymus plays an important role in the immune function of the body. We use inbred mice observed Mycobacterium tuberculosis infection on the thymus and found that mice infected with Mycobacterium tuberculosis H_ (37) Rv 3 weeks, the thymus decreased, the number of cells decreased. Experimental Methods I. Animal Origin: JCR and C57 (57) inbred mice supplied by the Laboratory Animal Center, Chinese Academy of Sciences, were about 20 grams in body weight and about 18 grams in C 57 (57). Second, grouping: each group of mice were 8 to 28. Each tuberculosis infection group and natural control group, for comparison. Third, the strain: standard human Mycobacterium tuberculosis (H_ (37) RV), in the improved Roche medium for the next generation of culture for 2 to 3 weeks to be rich in growth, with Health