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Objective: To investigate the role of MRI in the diagnosis of intracranial germinoma. Methods: MRI fea-tures of 19 cases of intracranial germinoma confirmed by operations and pathological findings were analyzed retrospec-tively. Results: Germinomas were found in the sellar region in 10 patients (including 5 males and 5 females), in thepineal region in 6 and in the thalamus and basal ganglia in 3, the 9 patients in the latter 2 groups all being males. Thecharateristic MRI findings of intracranial germinomas were as follows: (1)Lesions were isointense or slighly hypoin-tense on T_1WI while isointense or slightly hyperintense on T_2WI. The germinomas in the sellar region and pineal regionshowed no edema, but lesions in the thalamus basal ganglia showed mild to moderate edema and space-occupyingeffects. (2) Homogeneous or inhomogeneous Gd-DTPA enhancement were seen in most of the tumors. Conclusion:Multiaxial imaging and Gd-DTPA enhancement in MRI are helpful in the diagnosis and differentiation of intracra
Objective: To investigate the role of MRI in the diagnosis of intracranial germinoma. Methods: MRI fea-tures of 19 cases of intracranial germinoma confirmed by operations and pathological findings were analyzed retrospec- tively. Results: Germinomas were found in the sellar region in 10 The patients (including 5 males and 5 females), in the area of the pineal region in 6 and in the thalamus and basal ganglia in 3, the 9 patients in the latter 2 groups all being males. Thecharateristic MRI findings of intracranial germinomas were as follows: (1) Lesions were isointense or slighly hypoin-tense on T_1WI while isointense or slightly hyperintense on T_2WI. The germinomas in the sellar region and pineal regions show no edema, but lesions in the thalamus basal ganglia showed mild to moderate edema and space-occupyingeffects. (2) Homogeneous or inhomogeneous Gd-DTPA enhancement was seen in most of the tumors. Conclusion: Multiaxial imaging and Gd-DTPA enhancement in MRI are helpful in the diagnosis and different iation of intracra