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目的:探讨丁丙诺啡透皮贴剂治疗肩关节周围炎的患者对于疼痛的缓解效果和肩关节活动功能的改善作用。方法:搜集本院近5年来门诊就诊及住院治疗的肩周炎患者152例,全部患者均规范化按照VAS评分使用镇痛药物。其中,78例患者在达到中度及以上疼痛水平时,额外加用丁丙诺啡透皮贴剂。每隔3月通过电话随访量化患者疼痛评分变化情况,门诊随访检查患者肩关节活动功能,并使用Constant-Murley肩关节功能评分量表进行数字化评估。结果:152例肩周炎患者在治疗观察期间,疼痛及肩关节活动功能均有一定程度的缓解和改善,在观察期末,平均Constant-Murley肩关节功能评分保持于80分水平。在治疗观察期内,外用丁丙诺啡透皮贴的患者在6-18月期间时,Constant-Murley肩关节功能评分上升速度明显高于对照组(P<0.05)。结论:丁丙诺啡透皮贴剂可以加快肩周炎患者的康复速度,提升肩周炎患者在治疗期间的生活质量。
Objective: To investigate the effect of buprenorphine transdermal patch on pain relief and shoulder joint function in patients with periarthritis of the shoulder. Methods: A total of 152 patients with frozen shoulder who visited our hospital during the past 5 years and were hospitalized were enrolled. All patients were given standardized analgesics according to VAS score. Of these, 78 patients received additional buprenorphine transdermal patches when they achieved moderate and above-grade pain. Patient pain scores were quantified by telephone follow-up every three months. Outpatients were followed up for shoulder activity and were digitally evaluated using the Constant-Murley Shoulder Function Scale. Results: During the observation period, pain and shoulder joint function of 152 patients with frozen shoulder were relieved and improved to some extent. At the end of the observation period, the mean Constant-Murley shoulder function score maintained at 80 points. During the treatment observation period, the Constant-Murley shoulder joint function score was significantly higher in patients with transdermal buprenorphine than in the control group between June and August (P <0.05). Conclusion: Buprenorphine transdermal patch can speed up the recovery of patients with frozen shoulder and improve the quality of life of patients with frozen shoulder.