论文部分内容阅读
上腹部器官簇移植受者5例,其中男性4例,女性1例;胰腺癌肝转移3例,肝癌胰腺及腹腔淋巴结转移2例。5例患者分别于2004年5月至2005年4月接受上腹部器官簇移植治疗,切除脏器包括全胃、肝脏、胰腺、脾脏、十二指肠及部分空肠, 移植器官簇包括肝脏、胰腺、十二指肠及部分空肠。所有患者均于术后4~6h清醒, 8~14h撤除呼吸机;术后第3 ~7d从SICU转回普通病房开始康复治疗。AST、ALT及TB等肝功能指标在术后1周趋于正常水平;C-肽、血淀粉酶、血清胰岛素水平在1~2周内达到正常范围。目前,除1例患者出现肿瘤复发外,其余病例一般情况良好。肝胰十二指肠器官簇移植具有肿瘤根治彻底、器官功能替代全面的特点,是上腹部多脏器恶性肿瘤的有效治疗方法。
5 cases of upper abdominal organ transplant recipients, including 4 males and 1 females; 3 cases of hepatic metastases of pancreatic cancer, 2 cases of liver cancer pancreas and abdominal lymph node metastasis. Five patients underwent upper abdominal organ cluster transplantation from May 2004 to April 2005 respectively. The excised organs included the whole stomach, liver, pancreas, spleen, duodenum and part of the jejunum. The clusters of transplanted organs included the liver and pancreas , Duodenum and some jejunum. All patients were awake at 4 ~ 6h after operation and ventilator was removed at 8 ~ 14h. Patients were transferred from SICU to general ward after 3 ~ 7 days to begin rehabilitation. The indexes of liver function such as AST, ALT and TB tended to be normal one week after surgery. The C-peptide, serum amylase and serum insulin level reached the normal range within 1 to 2 weeks. At present, except one case of tumor recurrence, the rest of the cases are generally good. Hepatopancreaticoduodenal organ cluster transplantation with radical tumor radical, organ function to replace the full range of features, is an effective treatment of multiple organ malignancies in the upper abdomen.