This paper deals with the uplift mechanism and the uplift form of Qinghai-Xizang (Tibet) plateau and the deformation regularity of its surrounding region caused by this uplifting. It is shown that the insertion of Indian plate with the wedge-like frontal margin beneath Qinghai-Xizang plateau made the plateau compressed and uplifted; at same time along several pre-existing large faults, striking NE and NW, the strike-slip movement took place. It is of great significance to study Asian regional tectonics, especially to the present tectonic movement. This paper deals with the uplift mechanism and the uplift form of Qinghai-Xizang (Tibet) plateau and the deformation regularity of its surrounding region caused by this uplifting. It is shown that the insertion of Indian plate with the wedge-like frontal margin beneath Qinghai -Xizang plateau made the plateau compressed and uplifted; at same time along several several pre-existing large faults, striking NE and NW, the strike-slip movement took place. It is of great significance to study Asian regional tectonics, especially to the present tectonic movement.