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目的通过分析宫颈癌淋巴结转移与各临床病理因素的关系,探讨影响宫颈癌淋巴结转移的高危因素。方法收集2005年1月-2010年12月间行手术治疗的136例临床ⅠA-ⅡA期宫颈癌患者的临床病理资料,将淋巴结转移与各临床病理因素之间的关系进行单因素χ2检验及多因素logistic回归分析。结果总的淋巴结转移率为14.0%(19/136),其中以闭孔淋巴结转移为主(占63.2%),其次为髂内外淋巴结(占42.1%),而腹股沟深淋巴结、腹主动脉旁淋巴结均无转移。单因素分析显示临床分期、间质浸润深度、肿瘤病理类型、宫旁浸润、阴道浸润与淋巴结转移间具有相关性(P<0.05);而多因素分析显示仅临床分期、肿瘤病理类型、间质浸润深度与淋巴结转移相关。结论临床分期、肿瘤病理类型、间质浸润深度为淋巴结转移的高危因素。
Objective To analyze the relationship between cervical lymph node metastasis and clinicopathological factors and to explore the risk factors of cervical lymph node metastasis. Methods The clinicopathological data of 136 patients with stage ⅠA-ⅡA cervical cancer who underwent surgical treatment from January 2005 to December 2010 were collected. The relationship between lymph node metastasis and clinicopathological factors was analyzed by one-way χ2 test and multiple Logistic regression analysis. Results The total lymph node metastasis rate was 14.0% (19/136), of which the obstruction was mainly closed obturator lymph nodes (63.2%), followed by the internal and external iliac lymph nodes (42.1%), while the inguinal deep lymph nodes, paraaortic lymph nodes No transfer. Univariate analysis showed that the clinical stage, the depth of interstitial infiltration, tumor pathological type, paracancer infiltration, vaginal infiltration and lymph node metastasis were correlated (P <0.05), while multivariate analysis showed that only clinical stage, tumor pathological type, Invasion depth and lymph node metastasis. Conclusion The clinical stage, tumor pathological type and the depth of interstitial infiltration are the risk factors of lymph node metastasis.