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目的了解辽宁省葫芦岛市孕产妇梅毒感染流行状况,评价预防梅毒母婴传播干预措施的实施效果。方法对2011-2014年辽宁省葫芦岛市孕产妇梅毒检测资料,阳性孕产妇及其所生儿童实施综合干预措施情况进行分析。结果2011-2014年间,孕产妇梅毒检测阳性率从0.1%增长至0.4%,呈逐年上升趋势(趋势χ~2=42.16,P<0.001),2011-2014年共发现147例梅毒感染者,其中36例选择终止妊娠,111例选择继续妊娠,治疗率为100%,规范治疗率为26.1%。梅毒感染孕产妇分娩的111例婴儿中,死胎2例、7天内死亡2例、失访1例。检测106例满18个月的幼儿,先天梅毒7例(6.3%)、失访3例,儿童随访率达到97.1%。结论葫芦岛市孕产妇梅毒检测阳性率呈逐年上升趋势,通过全面开展预防梅毒母婴传播工作和落实综合干预措施,加强感染孕产妇治疗服务和暴露儿童随访管理,有效降低了先天梅毒的发生危险性。
Objective To understand the prevalence of syphilis infection among pregnant women in Huludao City of Liaoning Province and evaluate the effect of interventions to prevent mother-to-child transmission of syphilis. Methods 2011-2014 in Huludao City, Liaoning Province, pregnant women, syphilis test data, positive pregnant women and their children to implement comprehensive interventions were analyzed. Results During 2011-2014, the positive rate of syphilis testing increased from 0.1% to 0.4%, showing an upward trend year by year (trend χ ~ 2 = 42.16, P <0.001). A total of 147 cases of syphilis were detected in 2011-2014 36 cases chose to terminate the pregnancy, 111 cases choose to continue pregnancy, the treatment rate was 100%, the standard treatment rate was 26.1%. Syphilis infection in pregnant women delivery of 111 cases of infants, stillbirth in 2 cases, 2 cases died within 7 days, 1 case of missing. Detection of 106 cases of children over 18 months, 7 cases of congenital syphilis (6.3%), 3 cases of loss of follow-up, children’s follow-up rate reached 97.1%. Conclusions The detection rate of syphilis in pregnant women in Huludao City has been increasing year by year. The risk of congenital syphilis is effectively reduced by comprehensively preventing mother-to-child transmission of syphilis and implementing comprehensive interventions, strengthening treatment services for infected mothers and managing follow-up of exposed children Sex.