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目的探讨前颞海马杏仁核切除术式(CAH)对颞叶癫痫患者的精神症状的影响。方法 75例颞叶癫痫患者经历了CAH手术,并且3次(术前、术后1年、术后2年)顺利完成了SCL-90自评量表。统计分析患者的平均GSI(精神症状整体严重性)得分。结果患者术后1年和2年的平均GSI得分均低于术前。全体患者术后2年的平均GSI得分均低于术后1年。不同时期(术前、术后1年、术后2年)男女组之间,左右侧组之间以及头颅MRI正常和异常组之间的平均GSI得分均无显著性差异。结论 CAH术式可以改善颞叶癫痫患者术后的精神症状。这种改善与术后的疗效有关,而与性别、位置和MRI有无异常无关。
Objective To investigate the effect of anterior temporal hippocampus appendectomy (CAH) on mental symptoms in patients with temporal lobe epilepsy. Methods Seventy - five patients with temporal lobe epilepsy underwent CAH surgery. The SCL - 90 self - rating scale was successfully completed three times (preoperatively, one year after operation and two years after operation). Patients were statistically analyzed for mean GSI (overall severity of psychiatric symptoms) scores. Results The average GSI scores of patients at 1 year and 2 years after operation were lower than those before operation. The average GSI score of all patients after 2 years was lower than 1 year after operation. There were no significant differences in mean GSI scores between men and women, between left and right groups, and between normal and abnormal MRI groups in different periods (preoperative, postoperative 1 year and postoperative 2 years). Conclusion CAH can improve the mental symptoms of patients with temporal lobe epilepsy. This improvement is related to postoperative efficacy, regardless of gender, location, and presence or absence of MRI.