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目的对比研究治疗青少年抑郁症的理想疗法,探讨心理干预治疗青少年抑郁症的效果。方法选取我院于2009年1月-2012年2月确诊的16~24岁青少年抑郁症患者100例,随机分为观察组与对照组各50例。对照组单纯给予口服抗抑郁药物舍曲林治疗,观察组接受口服抗抑郁药物舍曲林治疗的同时联合心理干预疗法。分别于治疗前和治疗第2、4、8周末采用汉密尔顿抑郁量表(HAMD)评定治疗效果。结果连续治疗8周后,观察组有效率为92.0%,对照组有效率为78.0%,观察组有效率明显高于对照组,两组比较差异有统计学意义(χ2=6.442,P<0.05);治疗后两组HAMD评分与治疗前比较显著降低(P<0.05),观察组在治疗第2、4、8周末时HAMD评分与对照组比较差异均具有统计学意义(P<0.05)。结论与单纯的药物治疗相比较,药物治疗联合心理干预对治疗青少年抑郁症的疗效显著,起效快速,是治疗青少年抑郁症的理想方法之一。
Objective To compare the ideal therapy for treating depression in adolescents and explore the effect of psychological intervention on adolescent depression. Methods 100 cases of depression in our hospital aged from 16 to 24 years old diagnosed in our hospital from January 2009 to February 2012 were randomly divided into observation group and control group with 50 cases each. The control group was given oral antidepressant sertraline alone, and the observation group received oral antidepressant sertraline combined with psychological intervention. The therapeutic effect was assessed by Hamilton Depression Rating Scale (HAMD) before treatment and at the end of the 2nd, 4th, and 8th week respectively. Results After 8 weeks of continuous treatment, the effective rate was 92.0% in the observation group and 78.0% in the control group. The effective rate in the observation group was significantly higher than that in the control group (χ2 = 6.442, P <0.05) (P <0.05). The HAMD score of the two groups after treatment was significantly lower than that before treatment (P <0.05). The HAMD score of the observation group at the end of the 2nd, 4th and the 8th week was significantly lower than that of the control group (P <0.05). Conclusion Compared with the simple drug treatment, drug therapy combined with psychological intervention in the treatment of depression in children with significant effect, rapid onset, is an ideal method of treatment of depression in adolescents.