脑梗死是中老年人致死致残的主要疾病之一。近年来在脑梗死的治疗中应用盐酸纳洛酮已受到广泛重视。纳洛酮是通过抢先和阿片受体结合,阻断内源性阿片肽与中枢神经系统内的阿片受体结合而发挥其药理作用的。为探讨纳洛酮的临床疗效,我们取采随机对照的临床研究方法,观察了纳洛酮对早期脑梗死患者的治疗效果。 Cerebral infarction is one of the major diseases causing death and disability in the elderly. In recent years, the application of naloxone hydrochloride in the treatment of cerebral infarction has received widespread attention. Naloxone exerts its pharmacological action by preempting opioid receptors and blocking the binding of endogenous opioid peptides to opioid receptors in the central nervous system. To explore the clinical efficacy of naloxone, we take a randomized controlled clinical study to observe the effect of naloxone on patients with early cerebral infarction.