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目的观察分析凝血因子替代治疗下的血友病患者智齿拔除术的安全性及注意事项的探讨。方法回顾分析9例血友病患者的智齿拔除术,术前给予凝血因子替代治疗,术中及术后采用微创拔牙的处理方案。结果 9例共拔除智齿10颗,其中1例下颌阻生齿因次日仍有活动性出血再次给与凝血因子输入后止血,其余患者术后当天仅有少量渗血。结论血友病患者术前采用凝血因子替代治疗可以安全进行智齿拔除术。
Objective To investigate the safety and precautions of wisdom tooth extraction in hemophilia patients under the influence of coagulation factor replacement therapy. Methods Retrospective analysis of 9 cases of hemophilia patients with wisdom teeth removal, preoperative coagulation factor replacement therapy, intraoperative and postoperative use of minimally invasive extraction treatment. Results A total of 10 cases of wisdom teeth were removed in 9 cases. One case of mandibular incisors still had active hemorrhage on the next day and was given hemostatic factor again after the input of blood coagulation factors. The rest of patients received only a small amount of bleeding on the day after operation. Conclusion Hemophilia patients can be safely treated with wisdom factor removal by preoperative coagulation factor replacement therapy.