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失代偿期肝硬化患者易于并发各种感染性疾病,据报道,其中,以败血症居各并发症之首,发病率为20%。但各种感染性并发症的发病率亦不尽相同,有的以细菌性腹膜炎(SBP)为最,或以肺炎居首。若一旦并发败血症,同时并发 SBP 的机会增多。这种情况指的是失代偿期肝硬化患者,若代偿良好,并发败血症的频度不过1.1%。另外,据报道,在65例大肠杆菌败血症中,继发于肝胆疾病24例(36.9%),其中肝硬化竟有6例之多,另有暴发性肝炎1例。可见肝病与大肠杆菌败血症关系密切。引起败血症的病原菌在近些年来也发生了变化。以前几乎半数由肺炎球菌与溶血性链球菌引起,1/5
Patients with decompensated cirrhosis tend to be complicated by a variety of infectious diseases, of which sepsis is reported as the first of any complication, with an incidence of 20%. However, the incidence of various infectious complications are not the same, some with bacterial peritonitis (SBP) as the most, or with pneumonia. If concurrent sepsis, concurrent SBP opportunities increase. This situation refers to patients with decompensated cirrhosis, compensable, with sepsis frequency of only 1.1%. In addition, it is reported that in 65 cases of E. coli sepsis, secondary to hepatobiliary disease in 24 cases (36.9%), of which as much as cirrhosis in 6 cases, and another case of fulminant hepatitis. Liver disease can be seen closely related to E. coli sepsis. Pathogens causing sepsis have also changed in recent years. Almost half of the past caused by pneumococci and hemolytic streptococcus, 1/5