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目的评估分析持续正压通气(continuous positive airway pressure,CPAP)治疗对阻塞性睡眠呼吸暂停低通气综合征(obstructive sleep apnea hypopnea syndrome,OSAHS)合并牙周炎患者的效果,推断牙周炎与OSAHS潜在的相关关系。方法运用随机抽样的方法选取我院2013年1月至2015年1月收治的52例阻塞性睡眠呼吸暂停低通气综合征伴牙周炎患者和18名经门诊确诊的20~60岁非OSAHS单纯牙周炎患者及20名健康成人(均排除基础代谢类疾病),分别记为研究组(n=52)、对照组(n=18)和空白组(n=20)。对研究组患者进行CPAP治疗三个月,而让三组人群均自行一般牙周维护。结果研究组患者6个位点经CPAP治疗前后的PD差和AL差均显著大于对照组(P<0.05);研究组患者治疗前后的牙槽骨高度差大于对照组(P<0.05);研究组与对照组在治疗前牙周袋深度(PD)、附着丧失(AL)及牙槽嵴高度差异无统计学意义(P>0.05),空白组治疗前后PD差、AL差和牙槽骨高度差差异变化无统计学意义。结论 CPAP治疗方法在改善OSAHS患者通气状况的同时也能在一定程度上改善患者的牙周状况。
Objective To evaluate the effect of continuous positive airway pressure (CPAP) treatment on patients with chronic obstructive sleep apnea hypopnea syndrome (OSAHS) complicated with periodontitis and to infer the potential of periodontitis and OSAHS The relationship between. Methods Fifty-two patients with obstructive sleep apnea-hypopnea syndrome and periodontitis admitted from January 2013 to January 2015 in our hospital were selected by random sampling method and 18 non-OSAHS patients Patients with periodontitis and 20 healthy adults (all with underlying metabolic diseases excluded) were recorded as study group (n = 52), control group (n = 18) and blank group (n = 20). Patients in the study group were treated with CPAP for three months while the three groups were given general periodontal maintenance. Results The differences of PD and AL between 6 groups before and after CPAP were significantly higher in study group than those in control group (P <0.05). The height difference of alveolar bone in study group before and after treatment was significantly higher than that in control group (P <0.05) There was no significant difference in PD, AL and alveolar ridge height between the two groups before treatment (P> 0.05), before treatment and after treatment, the difference of PD, AL difference and alveolar bone height Difference difference has no statistical significance. Conclusions CPAP treatment can improve the periodontal status of patients with OSAHS to a certain extent while improving the ventilation of patients with OSAHS.