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目的观察银杏二萜内酯葡胺注射液治疗急性脑梗死的疗效及安全性。方法将80例急性脑梗死患者随机分为治疗组40例和对照组40例,治疗组采用银杏二萜内酯葡胺注射液进行静脉滴注,对照组采用银杏达莫注射液进行静脉滴注,疗程均为14 d。比较两组神经功能评分及临床疗效。结果治疗前两组神经功能缺损评分间差异无统计学意义(P>0.05);而治疗后治疗组神经功能缺损评分低于对照组(P<0.05)。两组临床疗效间差异有统计学意义(u=2.678,P=0.007)。结论银杏二萜内酯葡胺注射液治疗急性脑梗死安全有效,值得在临床上推广使用。
Objective To observe the efficacy and safety of ginkgo diterpene lactone meglumine injection in the treatment of acute cerebral infarction. Methods Eighty patients with acute cerebral infarction were randomly divided into treatment group (40 cases) and control group (40 cases). In the treatment group, ginkgo diterpene lactone diacetate injection was used for intravenous infusion, while in the control group, ginkgo dipyridamole injection was used for intravenous infusion , Treatment for 14 d. Neurological scores and clinical efficacy were compared between the two groups. Results There was no significant difference in neurological deficit score between the two groups before treatment (P> 0.05), but after treatment, the score of neurological deficit in the treatment group was lower than that of the control group (P <0.05). The difference between the two groups was statistically significant (u = 2.678, P = 0.007). Conclusion Ginkgo diterpene lactone meglumine injection in the treatment of acute cerebral infarction safe and effective, it is worth promoting in clinical use.