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目的:探讨乙型肝炎后肝硬化合并肝性脑病(HE)发生、发展的相关危险因素,并为临床制定该病的防治策略提供经验积累。方法:回顾性分析我院消化内科于2008年1月至2012年12月收治的64例乙肝后肝硬化合并HE患者,设为研究组。另外选取同期住院的53例乙肝后肝硬化未合并HE患者作为对照组。比较两组患者的客观生理指标,并做好记录。结论:对于乙肝后肝硬化合并肝性脑病患者而言,高龄、危险诱因数量及肝功能严重程度与疾病的发生和发展密切相关,积极去除诱因是治疗乙型肝炎后肝硬化合并HE的关键。
Objective: To explore the related risk factors for the occurrence and development of posthepatitic cirrhosis with hepatic encephalopathy (HE) in hepatitis B and to provide experience for the clinical prevention and treatment of this disease. Methods: A retrospective analysis of our hospital from January 2008 to December 2012 in the Department of Gastroenterology, 64 cases of patients with posthepatitis B liver cirrhosis complicated with HE, as the study group. In addition, 53 hospitalized patients with hepatitis B cirrhosis without HE were selected as the control group. The objective physiological indexes of two groups were compared and recorded. Conclusions: The number of advanced age, risk factors and the severity of liver function are closely related to the occurrence and development of disease in patients with posthepatitic cirrhosis complicated with hepatic encephalopathy. Active removal of inducement is the key to the treatment of posthepatitic cirrhosis with HE.