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单核细胞增多性李司忒菌(LM)系Gram(+)球菌,长约0.5～1.2μ,天然广泛存在于湿土、水、畜粪、草料中.经由病畜排泄物污染的食物可传染给人类,亦可经由创口、结合膜炎而感染.凡妊娠、肝硬化、免疫抑制剂(皮质类固醇、抗癌药物)均会促进LM感染.健康人带菌者在粪便中可找到LM.临床:一般起病急骤、严重,高热逾39℃,头痛剧烈.数天后始出现脑膜刺激征.神经症状特殊而严重,每集中于脑干颅神经损害,诸凡Ⅲ、Ⅳ、Ⅵ;Ⅶ、Ⅷ;Ⅴ、以及后组神经均可有不同组合的损害,一侧或双侧.小脑共济失调、平衡障碍.锥
Listeria monocytogenes (LM) is a strain of Gram (+) coccus, 0.5-1.2μ in length, naturally found in wet soil, water, livestock excrement and forage. Infected to humans, but also by the wounds, combined with meningitis and infection. Where pregnancy, cirrhosis, immunosuppressive agents (corticosteroids, anti-cancer drugs) will promote LM infection. Healthy human carriers can find LM in the stool. : General onset of sudden, severe, high fever over 39 ℃, severe headache. Meningeal irritation began to appear after a few days. Neurological symptoms of special and serious, each focus on brain stem cranial nerve damage, Zhu Fan Ⅲ, Ⅳ, Ⅵ; Ⅶ, Ⅷ ; Ⅴ, as well as the latter group of nerve can have different combinations of damage, one or both sides. Cerebellar ataxia, balance disorders.