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目的对比分析米索前列醇与小剂量缩宫素对足月妊娠引产的临床疗效。方法 160例符合引产指征的患者,随机分为观察组和对照组,各80例。观察组患者采用米索前列醇进行引产;对照组患者采用小剂量缩宫素进行引产。观察两组治疗效果。结果观察组引产总有效率为96.25%,对照组引产总有效率为77.50%,差异有统计学意义(χ2=12.33,P<0.01);观察组患者在用药后总产程及宫颈Bishop评分均优于对照组,差异有统计学意义(P<0.05);观察组患者顺产率为94.70%,对照组患者顺产率为63.30%,差异有统计学意义(χ2=25.25,P<0.01)。结论米索前列醇和小剂量缩宫素作为引产药,各具特点。其中,米索前列醇效果较小剂量缩宫素效果好,能明显缩短产程,显著提高顺产率,具有应用推广价值。
Objective To compare the clinical efficacy of misoprostol with low-dose oxytocin on term pregnancy induced labor. Methods A total of 160 patients with induction of labor induction were randomly divided into observation group and control group, 80 cases each. Patients in the observation group were treated with misoprostol for induction of labor; patients in the control group were treated with low-dose oxytocin for induction of labor. Observation of two groups treatment effect. Results The total effective rate of induction of labor was 96.25% in the observation group and 77.50% of the control group, the difference was statistically significant (χ2 = 12.33, P <0.01). The patients in the observation group were both better in terms of total labor and cervical Bishop score In the control group, the difference was statistically significant (P <0.05). In the observation group, the follow-up rate was 94.70% and that in the control group was 63.30%. The difference was statistically significant (χ2 = 25.25, P <0.01). Conclusion Misoprostol and low-dose oxytocin as abortion drugs, each with its own characteristics. Among them, misoprostol effect of smaller doses of oxytocin effect, can significantly shorten the labor process, significantly improve the yield, with the application of promotional value.