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重症狼疮性肾炎免疫炎症反应重,病程凶险,但多数患者病情都可有效控制。治疗以抑制免疫反应、保护器官功能、改善预后为目标,以提高患者生存质量为前提并且贯穿治疗的始终。重症狼疮性肾炎诱导治疗方案已有多样选择,需要根据狼疮性肾炎的病理分型、肾脏组织中狼疮活动的活动性和慢性指数、蛋白尿水平、肾功能、器官受累等情况综合考虑合理选用。
Severe lupus nephritis immune inflammation and heavy, dangerous course, but the majority of patients with disease can be effectively controlled. Treatment to suppress the immune response, protect organ function, improve the prognosis as the goal, to improve the quality of life of patients as the premise and throughout the treatment. Induction of treatment of lupus nephritis has been a variety of options, according to the pathological type of lupus nephritis, renal activity and chronic lupus activity and chronic index, proteinuria, renal function, organ involvement, etc. Consideration of the rational selection.