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目的探讨嗅神经母细胞瘤的CT和MRI影像特征,包括肿瘤部位、大小、累及范围、周围骨质破坏、密度及信号改变等。方法回顾性分析我院2003～2009年13例经手术或穿刺病理确诊的嗅神经母细胞瘤的CT和MRI表现。结果 13例患者CT平扫示肿瘤密度不甚均匀,与软组织密度接近,内可见斑片状低密度。MRI显示:T1WI表现为低于脑灰质的低信号病灶,T2WI信号较脑组织稍高。13例中10例伴有囊变坏死,T1WI呈不均匀低信号,T2WI不均匀高信号,增强扫描明显不均匀强化。肿瘤同时累及颅内外者11例,双侧额叶同时受累1例,右侧额叶受累6例,左额叶受累4例,脑组织水肿7例。结论嗅神经母细胞瘤的影像学表现无明显特异性,影像学检查可界定肿瘤累及范围及分期,对治疗方案的选择有重要价值。
Objective To investigate the CT and MRI features of olfactory neuroblastoma, including tumor location, size, extent of involvement, surrounding bone destruction, density and signal changes. Methods The CT and MRI findings of 13 cases of olfactory neuroblastoma confirmed by operation or puncture pathology in our hospital from 2003 to 2009 were retrospectively analyzed. Results The CT scan of 13 patients showed that the tumor density was not even, which was similar to the soft tissue density. MRI showed: T1WI showed lower signal lesions than gray matter, T2WI signal slightly higher than the brain tissue. Thirteen of 10 patients with cystic necrosis, T1WI showed a non-uniform low signal, T2WI uneven high signal, enhanced scan significantly uneven enhancement. There were 11 cases of intracranial and extracranial tumors, 1 case of bilateral frontal lobe involvement, 6 cases of right frontal lobe involvement, 4 cases of left frontal lobe involvement and 7 cases of brain edema. Conclusion The imaging findings of olfactory neuroblastoma have no obvious specificity. Imaging examination can define the extent and stage of tumor involvement, which is of great value in the selection of treatment options.