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目的:探讨三十五味沉香丸对小鼠的镇痛、抗炎作用,为临床合理用药提供参考依据。方法:将小鼠随机分为5组,即生理盐水对照组、三十五味沉香丸高、中、低(1.0g/kg、0.75g/kg、0.5g/kg)剂量组,西药(氨基比林、氢化可的松)组,灌胃给药,观察对小鼠的镇痛、抗炎作用。结果:三十五味沉香丸能明显提高小鼠的痛阈值,减少小鼠的自主活动次数。结论:三十五味沉香丸具有明显的镇痛、抗炎作用。
Objective: To investigate the analgesic and anti-inflammatory effect of thirty-five flavors and Fragrance Pills on mice and to provide a reference for rational clinical use. Methods: The mice were randomly divided into 5 groups: saline control group, Sanwuweixiangxiangwan high, medium and low dose groups (1.0g / kg, 0.75g / kg, 0.5g / Bering, hydrocortisone) group, intragastric administration, observe the analgesic and anti-inflammatory effects on mice. Results: Thirty Wuwei Shenxiang Pill can significantly increase the pain threshold in mice, reduce the number of spontaneous activity in mice. Conclusion: Thirty Wuwei Shenxiang pill has obvious analgesic and anti-inflammatory effects.