喉癌约占全身恶性肿瘤的5.7%～7.6%,其主要病理类型鳞状细胞癌约占93%以上〔1〕。典型喉癌的症状包括声音嘶哑、喉痛、呼吸困难或痰中带血,颈部出现肿块也是其常见症状。研究证明,喉癌的发生、发展是一个长时间、多阶段的过程,在细胞癌变的过程中,细胞周期中的多种调节因子参与 Laryngeal cancer accounts for about 5.7% of malignant tumors 7.6%, the main pathological type of squamous cell carcinoma accounts for about 93% 〔1〕. Symptoms of a typical laryngeal cancer, including hoarseness, sore throat, difficulty breathing or blood in the sputum, the neck appears mass is also a common symptom. Studies have shown that the occurrence and development of laryngeal cancer is a long, multi-stage process in the process of cancerization of cells, the cell cycle in a variety of regulatory factors involved