约25％甲状腺髓样癌有ret癌基因的遗传性缺失，现知一些非髓样癌同样有基因异常。甲状腺乳头状癌（PTC）常是散发的，偶也有家族性或伴有常染色体显性疾病，如高雪病和家族性息肉病。作者报道7个家族，其中至少有两个人患PTC。作者自1991～1996年收治的105例PTC病例中检出7个家 About 25% of thyroid medullary carcinomas have a hereditary loss of the ret oncogene. Some non-myeloid carcinomas are also known to have genetic abnormalities. Thyroid papillary carcinoma (PTC) is often sporadic, and sometimes has familial or accompanied by autosomal dominant diseases, such as high snow disease and familial polyposis. The authors reported on seven families, at least two of whom had PTC. The author detected 7 homes from 105 PTC cases admitted from 1991 to 1996