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Mitochondrion provides much of the energy for the cell and the disorder in mitochondrion can affect almost any tissue [1].The mitochondrial DNA (mtDNA) covers 16,569 bp,consisting of 37 genes and 1 D-Loop region in human.Mitochondrion is unique in possessing their own genome which is organized into mitochondrial nucleoids by employing multiprotein machineries,and can perform the functions of gene replication,transcription,and repair [2].