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目的了解老年病科住院患者骨质疏松症患病率,并探讨其与心血管疾病危险因素的关系。方法选取2012年9月—2015年8月在华中科技大学同济医学院附属梨园医院老年病科住院的患者943例,根据是否患有骨质疏松症分为骨质疏松症组(OP组,n=387)和非骨质疏松症组(NOP组,n=556)。自制的调查问卷调查患者的人口学资料,对患者进行体格检查,记录两组患者的心血管疾病危险因素,骨质疏松症的影响因素分析采用多因素logistic回归分析。结果 943患者中骨质疏松症387例,骨质疏松症患病率为41.04%。两组患者年龄及冠心病、脑卒中、心力衰竭发生率比较,差异无统计学意义(P>0.05);OP组患者女性所占比例、吸烟率及糖尿病、高血压、高脂血症发生率高于NOP组,体质指数(BMI)低于NOP组(P<0.05)。多因素logistic回归分析结果显示,女性、吸烟、糖尿病、高血压、高脂血症是骨质疏松症的危险因素(P<0.05)。结论老年病科住院患者骨质疏松症患病率较高,且与心血管病危险因素密切相关,应采取系统全身性措施进行预防和治疗。
Objective To understand the prevalence of osteoporosis in geriatric inpatients and explore its relationship with cardiovascular risk factors. Methods Nine hundred and seventy-three patients were enrolled in the Department of Geriatrics, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology from September 2012 to August 2015. They were divided into osteoporosis group (OP group, n = 387) and non-osteoporosis group (NOP group, n = 556). Self-made questionnaire survey of patients with demographic data, physical examination of patients, record of cardiovascular risk factors in two groups of patients, analysis of factors affecting osteoporosis using multivariate logistic regression analysis. Results Among the 943 patients, 387 were osteoporosis and the prevalence of osteoporosis was 41.04%. There was no significant difference in the age, coronary heart disease, stroke and heart failure between the two groups (P> 0.05). The proportion of women in the OP group, the prevalence of smoking and the incidence of diabetes, hypertension and hyperlipidemia Higher than NOP group, body mass index (BMI) was lower than NOP group (P <0.05). Multivariate logistic regression analysis showed that female, smoking, diabetes, hypertension and hyperlipidemia were the risk factors of osteoporosis (P <0.05). Conclusions The prevalence of osteoporosis in geriatric inpatients is high and closely related to the risk factors of cardiovascular disease. Systemic systemic measures should be taken to prevent and treat osteoporosis.