论文部分内容阅读
目的:探讨全结肠系膜切除术(CME)治疗进展期结肠癌患者的效果及对肠胃功能和血清T淋巴细胞亚群的影响。方法:抽取2017年1月至2020年1月南阳市第二人民医院收治的进展期结肠癌患者80例，依据手术方案分为两组，每组40例。对照组采取传统开腹手术治疗，研究组采取CME治疗。统计两组围术期情况、术后1个月统计肛门功能优良率、术前及术后1、2 d T淋巴细胞亚群指标、并发症发生率。结果:研究组术中失血量少于对照组，胃肠功能恢复时间、下地活动时间、住院时间短于对照组(n P<0.05)；研究组肛门功能优良率高于对照组(n P<0.05)；术后不同时间段研究组CD3n ＋、CD4n ＋、CD4n ＋/CD8n ＋水平高于对照组(n P<0.05)；研究组并发症发生率低于对照组(n P<0.05)。n 结论:CME治疗进展期结肠癌，能有效减少术中失血量，促进胃肠功能恢复，缩短下地活动时间、住院时间，提高肛门功能恢复效果，减轻免疫应激，降低并发症发生风险。“,”Objective:To investigate the effect of complete mesocolic excision (CME) in the treatment of patients with advanced colon cancer and its influence on gastrointestinal function and serum T lymphocyte subsets.Methods:A total of 80 patients with advanced colon cancer in the Second People’s Hospital of Nanyang from January 2017 to January 2020 were selected and divided into two groups according to the surgical plan, with 40 cases in each group. The control group was treated with traditional open surgery and the study group was treated with CME. The perioperative conditions and the excellent and good rate of anal function 1 month after surgery, T lymphocyte subgroup indexes before operation and 1 day and 2 days after operation, the incidence of complications were counted in the two groups.Results:The blood loss during the operation in the study group was less than that in the control group, and the recovery time of gastrointestinal function, the time of ground activity, and the length of hospital stay were shorter than those of the control group (n P<0.05); the excellent and good rate of anal function in the study group was higher than that in the control group (n P<0.05); the levels of CD3n +, CD4n +, CD4n +/CD8n + in the study group were higher than those in the control group at different time periods after operation (n P<0.05); the incidence of complications in the study group was lower than that in the control group (n P<0.05).n Conclusions:In the treatment of advanced colon cancer, CME can effectively reduce intraoperative blood loss, promote the recovery of gastrointestinal function, and shorten the time of ground activity and hospitalization, improve the recovery effect of anal function, reduce immune stress, and reduce the risk of complications.