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目的观察泮托拉唑钠治疗十二指肠溃疡的临床效果。方法将十二指肠溃疡患者88例,无规则均分为试验组和对照组各44例。试验组给予泮托拉唑钠治疗,对照组给予奥美拉唑钠治疗,2组均治疗4周。对比2组患者的治疗效果、疼痛消失时间和不良反应发生率。结果试验组总有效率为97.73%,对照组总有效率为95.45%,2组总有效率比较差异无统计学意义(P>0.05)。试验组疼痛感消失时间为(4.31±1.26)d明显短于对照组的(7.56±1.49)d,差异有统计学意义(P<0.05)。2组不良反应发生率比较差异无统计学意义(P>0.05)。结论泮托拉唑钠治疗十二指肠溃疡疗效显著,不良反应较少,且可以减轻患者疼痛,值得临床推广应用。
Objective To observe the clinical effect of pantoprazole sodium in the treatment of duodenal ulcer. Methods 88 cases of duodenal ulcer patients were randomly divided into experimental group and control group, 44 cases each. The experimental group was treated with pantoprazole sodium, the control group was treated with omeprazole sodium, and the two groups were treated for 4 weeks. Comparison of two groups of patients with treatment, pain disappear time and adverse reactions. Results The total effective rate was 97.73% in the experimental group and 95.45% in the control group. There was no significant difference in the total effective rate between the two groups (P> 0.05). The pain disappearance time in the experimental group was significantly shorter than that in the control group at (4.31 ± 1.26) d and (7.56 ± 1.49) days, respectively, with significant difference (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). Conclusion Pantoprazole sodium treatment of duodenal ulcer significant effect, fewer adverse reactions, and can reduce pain in patients, it is worth promoting the clinical application.