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目的 :观察脂清冲剂对实验性家兔动脉粥样硬化的作用。方法 :用食饵性高脂家兔模型研究脂清冲剂对脂质代谢脂质过氧化及主动脉粥样斑块形成的影响。结果:脂清冲剂可降低高脂饲料6周或13周家兔的血清甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDLC)以及丙二醛(MDA)的含量;提高高密度脂蛋白胆固醇(HDLC)的含量;同时明显降低肝脏TG含量并减轻主动脉斑块病变程度。结论:脂清冲剂对实验性家兔动脉粥样硬化有一定的防治作用
Objective: To observe the effect of Zhiqing Granules on atherosclerosis in experimental rabbits. METHODS: The effect of Zhiqing powder on the lipid peroxidation of lipids and the formation of aortic atherosclerotic plaques was studied in a prey-fat high-fat rabbit model. RESULTS: Zhiqing Granules could reduce serum triglyceride (TG), total cholesterol (TC), low density lipoprotein cholesterol (LDLC) and malondialdehyde (MDA) in rabbits fed with high-fat diet for 6 or 13 weeks. Increase the content of high-density lipoprotein cholesterol (HDLC); also significantly reduce liver TG content and reduce the extent of aortic plaque disease. Conclusion: Zhiqing Granules have certain preventive and therapeutic effects on experimental atherosclerosis in rabbits