论文部分内容阅读
目的观察唑来膦酸联合VAD方案化疗治疗多发性骨髓瘤骨疼疗效。方法将确诊后的多发性骨髓瘤骨疼的患者随机分2组,每组20例。唑来膦酸组联合VAD方案,对照组单纯VAD(长春新碱+阿霉素+地塞米松)方案化疗。观察骨疼效果。结果唑来膦酸联合VAD组骨疼缓解率为95,单纯化疗组缓解率86。结论唑来膦酸联合VAD化疗治疗多发性骨髓瘤骨疼的缓解率较单纯化疗组高,差异有统计学意义。
Objective To observe the curative effect of zoledronic acid combined with VAD regimen chemotherapy for multiple myeloma bone pain. Methods The patients with multiple myeloma bone pain after diagnosis were randomly divided into two groups, 20 cases in each group. ZOL group combined VAD program, the control group of simple VAD (vincristine + doxorubicin + dexamethasone) regimen chemotherapy. Observe the effect of bone pain. Results The response rate of osteoporosis to zoledronic acid combined with VAD group was 95 and that of chemotherapy alone group was 86. Conclusion The response rate of zoledronic acid combined with VAD chemotherapy for treatment of multiple myeloma bone pain is higher than the chemotherapy alone group, the difference was statistically significant.