目的探讨输尿管硬镜钬激光碎石术治疗输尿管结石的有效性和安全性。方法回顾性分析116例输尿管硬镜钬激光碎石术治疗的输尿管结石患者资料。结果单次碎石成功率为96.5%(112/116),其中,上段结石单次成功率为76.4%(13/17),中、下段100%(99/99)。平均手术时间为35min,平均住院时间3.5d;术后随访2～8周,结石排净为97.3%(109/112)。结论输尿管硬镜钬激光碎石术治疗输尿管结石安全、有效,尤其适用于输尿管中、下段结石。 Objective To investigate the effectiveness and safety of ureteroscopic holmium laser lithotripsy in the treatment of ureteral calculi. Methods The clinical data of 116 patients with ureteral calculi treated by ureteroscopic holmium laser lithotripsy were retrospectively analyzed. Results The success rate of single gravel was 96.5% (112/116). Among them, the single success rate was 76.4% (13/17) in the upper segment and 100% (99/99) in the middle and lower segments. The average operation time was 35 minutes and the average length of hospital stay was 3.5 days. The patients were followed up for 2 to 8 weeks and the stone discharge was 97.3% (109/112). Conclusion ureteroscopic holmium laser lithotripsy for the treatment of ureteral stones safe and effective, especially for the ureter, lower stones.