作者报告1例罕见的色素性 Bowen 病,并对420例 Bowen 病例进行了回顾性研究。患者,87岁,意大利白人妇女。因环指有不常见的色素改变而就诊。10年前病人已发现在其左手环指有些鳞屑和开裂,但一直未重视。6个月前她开始发现损害颜色日益变暗。检查病人左环指有一色素增深的鳞屑性斑块,它经过相邻的指蹼而扩展到中指。损害内个别部位呈粉红色,大部分为巧克力样深棕色。损害无结节亦不硬,未发现相关淋巴结肿大,临床疑为表浅扩散的黑素瘤。病理报告为“鳞状细胞原位癌”。由于临床与组织学明显不符,作者又从环指 The authors reported a rare case of pigmented Bowen disease and retrospectively studied 420 Bowen cases. Patient, 87 years old, Italian white woman. Treatment for unusual pigment changes in the ring finger. Ten years ago the patient had noticed some scaling and cracking in his left hand ring finger, but he had not paid attention. Six months ago she began to find that the damage color was becoming darker. Examination of the patient’s left ring refers to a pigmented, enlarged scale-like plaque that extends to the middle finger through the adjacent palate. Individual parts of the lesion appear pink, most of which is chocolate-like dark brown. No nodules were damaged or hard, no related lymphadenopathy was found, and clinically suspected superficially diffuse melanoma. The pathology report was “squamous cell carcinoma in situ.” Because of the apparent discrepancy between clinical and histological studies, the