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运用病理切片和HE染色技术,对维氏气单胞菌自然感染大鲵的肌肉、肝、肾、肺、肠道等器官的组织病理学变化进行了观察。结果显示,肝可见大量淋巴细胞和少量中性粒细胞,肝细胞空泡状变性,肝血窦内见大量血细胞;肾集合管中可见少量蛋白样物,血管球扩张,有的溶解坏死;心肌纤维溶解,甚至坏死,可见充血和出血;胰细胞颗粒变性;肺偶见充血;脾索排列紊乱,脾窦中充满大量红细胞和巨噬细胞;肠道内肠绒毛溶解脱落,有充血现象;肌纤维蜡样坏死,肌细胞核浓缩凝固,深染,破碎。证实,维氏气单胞菌能使中国大鲵的多个组织器官出现严重的病理变化而导致死亡。
Histopathological changes of muscle, liver, kidney, lung, intestine and other organs of Aeromonas sobria naturally infected by Aeromonas sobria were observed by pathological sections and HE staining. The results showed that a large number of lymphocytes and a small amount of neutrophils were seen in the liver, and the hepatocytes were vacuolar degeneration. A large number of blood cells were seen in the hepatic sinusoid; a few protein samples were seen in the renal collecting tube, the vessels were dilated and some were lysed and necrotic; Muscle fibers dissolved, or even necrosis, congestion and bleeding can be seen; pancreatic granular degeneration; sporadic occasional congestion of the lungs; splenic cord disorder, the spleen sinus is filled with a large number of red blood cells and macrophages; enteric intestinal villi dissolve shedding, congestion phenomenon; muscle fiber wax Like necrosis, muscle cell nuclei condensed coagulation, deep-dyeing, broken. Confirmed that Aeromonas sobria can make a large number of tissues and organs of China’s big serious pathological changes lead to death.