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目的:分析胰岛素、磺脲类药物在与二甲双胍联合用药情况下治疗初发2型糖尿病的临床用药方式和效果。方法:研究资料为我院在2013年1月至2014月的80例初发性2型糖尿病患者治疗情况,将病患分为对照组和观察组各40例,其中观察组运用胰岛素与二甲双胍联合治疗,对照组运用磺脲类药与二甲双胍联合治疗,而后对比两组病患治疗后的血糖情况,以及并发症情况。结果:无论是空腹血糖、餐后血糖还是糖化血红蛋白情况上,观察组的改善情况均优于对照组;同时并发症发生率上,观察组为45%,对照组为92.5%。结论:二甲双胍与胰岛素联合用药治疗初发性的2型糖尿病,可以有效的控制血糖等相关指标,改善明显,同时并发症相对较少,治疗治疗保障性更高。
Objective: To analyze the clinical application of insulin and sulfonylurea in the treatment of newly diagnosed type 2 diabetes in combination with metformin. Methods: The data were 80 cases of primary type 2 diabetes mellitus in our hospital from January 2013 to April 2014, the patients were divided into control group and observation group of 40 cases, the observation group using insulin and metformin combination In the control group, sulfonylurea and metformin were used in the control group, and then the blood glucose level and complication of the two groups were compared. Results: Both fasting blood glucose, postprandial blood glucose and glycosylated hemoglobin were better in the observation group than in the control group. The incidence of complications was 45% in the observation group and 92.5% in the control group. Conclusion: The combination of metformin and insulin in the treatment of primary type 2 diabetes mellitus can effectively control the blood glucose and other related indicators, improve the obvious, at the same time the complication is relatively less, and the therapy is more protective.