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作者对4例脑膜炎球菌性脑膜炎合并关节炎或皮肤血管炎的患者进行了免疫学研究。血清脑膜炎球菌抗原应用免疫电泳法测定,血清抗体采用血凝试验,血清C_3补体用放射免疫弥散法测定。发现各例在症状出现的同时,血液中均有脑膜炎球菌循环抗原存在,1～4天后即消失;其中3例于发病一周左右测出循环抗体。3例在并发症出现时血清C_(?)补体水平下降,以后几天内逐渐上升;其中2例C_(?)补体显著下降,此时循环中抗原消失。此2例变态
The authors conducted immunological studies in 4 patients with meningococcal meningitis with arthritis or cutaneous vasculitis. Serum meningococcal antigen was detected by immunoelectrophoresis, serum antibody was determined by hemagglutination test, serum C_3 complement was determined by radioimmunoassay. In each case, meningococcal circulating antigens were found in all cases at the same time of symptom onset and disappeared after 1 to 4 days. Three of them were detected circulating antibodies within one week of onset. Serum C_ (?) Complement levels decreased in 3 cases when complications occurred, and gradually increased in the next few days; 2 cases of C_ (?) Complement decreased significantly, and the antigen disappeared in the circulation. The two cases metamorphosis