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目的比较热带地区痛风及类风湿性关节炎患者的生化指标差异。方法 2014年1月—2016年12月间在某院住院治疗的海南痛风患者816例及类风湿性关节炎患者316例,对其部分生化指标进行比较分析,利用统计学软件SPSS19.0对组间数据进行分析。结果两组患者鳞状上皮细胞、非鳞状上皮细胞、尿粘液、尿蛋白、尿液酸碱度、血清尿酸、钙、钾、磷、氯、钠都存在组间统计学差异(P<0.05)。其中痛风组中尿蛋白的检出率为43.1%,为类风湿性关节炎组的检出率(23.4%)的1.84倍。尿酸在男性痛风组中的浓度为(446±141.1)μmol/L,在男性风湿性关节炎患者中的浓度为(315.44±156.55)μmol/L;在女性痛风患者中的浓度为(382.7±123)μmol/L,在女性类风湿性关节炎患者中为(223±94.7)μmol/L;钙浓度在痛风组和风湿组中分别为(2.03±0.19)mmol/L和(1.99±0.18)mmol/L,差异有统计学意义(P<0.01)。结论临床生化指标差异不能作为2种病症的鉴别诊断依据。
Objective To compare the differences of biochemical indexes in patients with gout and rheumatoid arthritis in the tropics. Methods A total of 816 Hainan gout patients and 316 rheumatoid arthritis patients hospitalized in a hospital from January 2014 to December 2016 were enrolled in this study. Some biochemical indexes were compared and analyzed. Statistical software SPSS19.0 Between the data analysis. Results The squamous epithelial cells, nonsquamous epithelial cells, urine mucus, urinary protein, urine pH, serum uric acid, calcium, potassium, phosphorus, chlorine and sodium in the two groups were statistically different between the two groups (P <0.05). The detection rate of urinary protein in gout group was 43.1%, which was 1.84 times of that in rheumatoid arthritis group (23.4%). Uric acid was (446 ± 141.1) μmol / L in the male gout group and (315.44 ± 156.55) μmol / L in the male rheumatoid arthritis group, and 382.7 ± 123 in the female gout group ) (μmol / L) were (223 ± 94.7) μmol / L in patients with rheumatoid arthritis and 2.03 ± 0.19 mmol / L and 1.99 ± 0.18 mmol / L in patients with rheumatoid arthritis / L, the difference was statistically significant (P <0.01). Conclusion The difference of clinical biochemical indexes can not be used as the basis for the differential diagnosis of the two diseases.