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目的探讨妊娠期及产后妇女高危型人乳头状瘤病毒(HR-HPV-DNA)检测的临床意义。方法采用HC-Ⅱ检测妊娠及产后711例宫颈分泌物的HR-HPV-DNA。结果711份标本中,HR-HPV感染率15.07%,孕期及产后分别为15.92%、10.11%;<30岁13.43%,>30岁17.53%;5个年龄组分别为17.65%、13.01%、14.88%、21.57%、46.67%。结论HR-HPV感染率与我国流行病学调查比较,结果一致;产后比妊娠期低,但差异无统计学意义;在各年龄组之间比较差异有统计学意义,妊娠期宫颈癌筛查是安全可行、必要的。
Objective To investigate the clinical significance of detecting HR-HPV-DNA in pregnant and postpartum women. Methods HR-HPV-DNA of 711 cervical secretions during pregnancy and postpartum was detected by HC-Ⅱ. Results Among 711 specimens, HR-HPV infection rate was 15.07%, pregnancy rate and postpartum were 15.92% and 10.11% respectively; 13.43% and <30 years old and 17.53% respectively, and 17.65%, 13.01% and 14.88 %, 21.57%, 46.67%. Conclusion The prevalence of HR-HPV infection is similar to that of epidemiological survey in China. The postpartum birth rate is lower than that of pregnancy, but the difference is not statistically significant. There is significant difference among all age groups. The screening of cervical cancer in pregnancy is Safe and feasible, necessary.