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目的探讨不同体质量指数多囊卵巢综合征患者的内分泌和代谢特点。方法选取234例多囊卵巢综合征患者,分为肥胖组(n=74),非肥胖组(n=160),所有患者均检测黄体生成素(LH)、卵泡刺激素(FSH)、催乳素(PRL)、雌二醇(E2)、睾酮(T)、及空腹胰岛素、雄烯二酮(A2)、空腹血糖(FPG),并进行。结果与非肥胖组比较,肥胖组具有较低的FSH、E2,具有较高的体质量指数(BMI)、LH、PRL、T、A2、胰岛素抵抗指数(IR),差异均具有统计学意义(P<0.05)。肥胖组与非肥胖组比较具有较高的空腹胰岛素水平,差异有统计学意义(P<0.05)。结论肥胖多囊卵巢综合征患者易合并高雄激素血症,为严重的胰岛素抵抗。
Objective To investigate the endocrine and metabolic characteristics of patients with different body mass index of polycystic ovary syndrome. Methods 234 patients with PCOS were divided into obesity group (n = 74) and non-obese group (n = 160). All patients were tested for LH, FSH, (PRL), estradiol (E2), testosterone (T), fasting insulin, androstenedione (A2) and fasting blood glucose (FPG) Results Compared with non-obese group, obese patients had lower FSH and E2, higher body mass index (BMI), LH, PRL, T, A2 and insulin resistance index (IR) P <0.05). Obesity group and non-obese group had higher fasting insulin levels, the difference was statistically significant (P <0.05). Conclusion Obese polycystic ovary syndrome patients with easy hyperandrogenism, severe insulin resistance.