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肿瘤转移是恶性肿瘤的特征性生物学行为之一,也是导致肿瘤预后差的重要原因。其中,肿瘤细胞本身的运动能力增强是导致肿瘤侵袭性生长和远处迁移的前提,任何参与改变细胞运动能力的分子都有可能是导致肿瘤转移的关键分子。肌动蛋白(actin)表达量及其空间排布是引起细胞运动能力
Tumor metastasis is one of the characteristic biological behaviors of malignant tumors and also an important reason leading to poor tumor prognosis. Among them, the enhancement of the motility of the tumor cells itself is the prerequisite for tumor aggressive growth and distant metastasis. Any molecule involved in altering cell motility may be the key molecule that causes tumor metastasis. Actin expression and its spatial arrangement is caused by cell motility