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目的探讨Ⅱ型呼吸衰竭的临床治疗。方法通过对30例慢性阻塞性肺疾病伴Ⅱ型呼吸衰竭的患者在常规治疗的基础上,运用纳洛酮治疗的临床疗效观察及30例Ⅱ型呼吸衰竭的患者在常规治疗的基础上加用烟酰乙胺、祛痰碱2种呼吸兴奋剂进行临床疗效观察。结果30例患者治疗组显效20例,有效7例,总有效率90%,病死率10%,对照组中有效率63.3%,病死率36.7%。结论Ⅱ型呼吸衰竭的患者在常规治疗的基础上加用纳洛酮,可使患者呼吸困难症状明显改善,而且纳洛酮使用方便,静脉用药安全,目前未发现任何副反应,特别是在缺乏机械通气的基层医院,值得推广应用。
Objective To investigate the clinical treatment of type Ⅱ respiratory failure. Methods 30 cases of chronic obstructive pulmonary disease with type Ⅱ respiratory failure in patients on the basis of conventional treatment, the use of naloxone treatment of clinical efficacy and 30 cases of type Ⅱ respiratory failure in patients with conventional treatment based on the use of Nicotinic acid ethylamine, expectorant alkaloids 2 kinds of respiratory stimulants for clinical efficacy. Results In the 30 patients, the treatment group was markedly effective in 20 cases and effective in 7 cases. The total effective rate was 90% and the case fatality rate was 10%. The effective rate was 63.3% and the mortality rate was 36.7% in the control group. Conclusions Patients with type Ⅱ respiratory failure who use naloxone on the basis of routine treatment can significantly improve their symptoms of dyspnea. Moreover, naloxone is easy to use and safe for intravenous administration. No side effects have been found so far, especially in the absence of Mechanical ventilation of the grass-roots hospitals, it is worth promoting the application.