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为尽快研制成高效、无毒、价格低廉的新型杀精子剂，我们从５０余种传统中草药中筛选出杀精效果较好（ｌ分钟内使精子瞬间失活）的中药乌梅。经化学分析、提纯，确定其杀精有效成分为枸椽酸。其最低有效杀精浓度为０．０９％，经透射电镜观察证明：乌梅─枸椽酸杀伤精子的主要靶结构是精子顶体、质膜、核膜及线粒体，损伤核的遗传物质，使线粒体空泡变性，嵴崩解或者溶解。并证明乌梅─枸椽酸药液的浓度不同，上述结构损伤程度也不同。
In order to develop as soon as possible a new type of spermicide that is highly effective, non-toxic, and inexpensive, we have selected more than 50 kinds of traditional Chinese herbal medicines, Wumei, which has a good killing effect (immediately inactivates the sperm within 1 minute). After chemical analysis and purification, it was determined that the effective ingredient for killing sperm was tannic acid. The lowest effective spermicidal concentration was 0.09%. Transmission electron microscope observation showed that the main target structure of spermatozoa killing sperm was acrosome, plasma membrane, nuclear membrane and mitochondria of sperm, which damaged the genetic material of the nucleus and made mitochondria. Cavitation degeneration, disintegration or dissolution. It also proves that the concentration of the Wumei-citric acid solution is different, and the damage degree of the structure is also different.