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患者男,40岁。右手拇指背侧出现红色斑块2年余。皮损组织病理示:角化过度,角化不全,表皮不规则向下增生,真皮内可见弥漫混合炎症细胞浸润。PAS染色可见多个厚壁、分隔的圆形或椭圆形暗色真菌孢子浸润到真皮和皮下脂肪组织,个别孢子已进入血管。真菌种属鉴定示:球孢枝孢。诊断:球孢枝孢所致皮肤着色真菌病。
Male patient, 40 years old. Right thumb red dorsal appear more than 2 years. Histopathological lesions showed: hyperkeratosis, keratosis, epidermal irregular downward hyperplasia, diffuse mixed inflammatory cell infiltration can be seen in the dermis. PAS staining revealed multiple thick, separated round or oval dark fungal spores infiltrating dermal and subcutaneous adipose tissue, individual spores have entered the blood vessels. Identification of fungal species showed: spores Cladosporium. Diagnosis: Coccidioides caused by skin fungal skin disease.