论文部分内容阅读
目的探讨缺血性脑卒中患者C!反应蛋白(CRP)与动脉粥样硬化程度的关系。方法选择住院确诊为缺血性脑卒中患者150例,行颈动脉超声多普勒检查,根据颈动脉超声检查的结果分为颈动脉狭窄组、颈动脉内膜斑块形成组、颈动脉内膜正常组,应用德国BNProSpec系统以散射比浊法测定血清CRP浓度,进行组间比较。结果颈动脉狭窄组的CRP为(12.163±1.407)mg/L,高于颈动脉内膜正常组〔(1.593±0.120)mg/L〕和颈动脉内膜斑块形成组〔(5.027±0.557)mg/L〕,有显著性差异(P<0.05),余组间比较无显著性差异(P>0.05)。结论颈动脉病变程度与血清CRP水平密切相关,将二者结合起来,对缺血性脑卒中的预防、治疗及判断预后有重要意义。
Objective To investigate the relationship between C-reactive protein (CRP) and the degree of atherosclerosis in patients with ischemic stroke. Methods 150 hospitalized patients with ischemic stroke were selected and underwent Doppler ultrasound examination of carotid artery. According to the results of carotid ultrasound examination, they were divided into carotid artery stenosis group, carotid artery intimal plaque formation group, carotid artery intima In the normal group, serum BNP concentration was measured by nephelometry using Germany BNProSpec system and compared between groups. Results The CRP in carotid stenosis group was (12.163 ± 1.407) mg / L, higher than that in carotid endarterectomy normal group (1.593 ± 0.120 mg / L) and carotid intimal plaque formation group (5.027 ± 0.557) mg / L], there was significant difference (P <0.05), no significant difference between the other groups (P> 0.05). Conclusion The degree of carotid artery disease is closely related to the level of serum CRP. Combining the two can be of great significance in the prevention, treatment and prognosis of ischemic stroke.