女性,1岁10个月。生后7个月开始经常出现皮肤紫癜,轻微损伤即出血不止。1岁时因摔倒致鼻出血10余小时不止而住院治疗,经用安络血、止血敏、维生素C、局部压迫和输血200ml方止血。此后仍常有出血不止及大片皮下紫癜史。患儿系第一胎第一产,足月顺产。生长发育史正常,父母非近亲 Female, 1 year old and 10 months old. 7 months after birth often appear skin purpura, mild bleeding that is more than bleeding. At the age of 1 due to falls caused by nose bleeding more than 10 hours in hospital, by the use of collateral blood, bleeding sensitivity, vitamin C, local oppression and blood transfusion 200ml side to stop bleeding. Since then there is often bleeding and large subcutaneous purpura history. The first birth of children in the first birth, full-term birth. Growth and development history is normal, non-relatives of parents