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目的了解经尿道前列腺电切围手术期抗菌药物的使用情况,为临床合理用药提供指导。方法对2005年8月-2009年8月经尿道前列腺电切手术抗菌药物的使用进行回顾性调查、分析。结果 352例经尿道前列腺电切术均应用抗菌药物,使用率达100.00%,抗菌药物以头孢羟氨苄(30.68%)为最多,氨曲南(4.83%)最少;术前30 min给药为最多,为267例,占75.85%;抗菌药物应用疗程为3~10 d,平均5.3 d,疗程3 d为最多,占60.23%,疗程10 d为最少,占12.78%;术后医院感染率为4.26%。结论医院对经尿道前列腺电切术抗菌药物的应用给药时间和疗程较为规范、合理,医院感染率控制在较低水平,但预防用药的类别比较高,有待于进一步控制。
Objective To understand the use of antimicrobial agents during transurethral electrovaporization of the prostate to provide guidance for rational clinical use. Methods The retrospective investigation and analysis of the use of transurethral resection of prostate cancer from August 2005 to August 2009 were performed. Results All the 352 cases of transurethral resection of prostate were treated with antimicrobial agents, with a rate of 100.00%. The antibacterials were cefadroxil (30.68%) and aztreonam (4.83%) the least. Accounting for 75.85% of the total. The duration of antimicrobial treatment was 3 to 10 days (mean 5.3 days). The duration of antimicrobial treatment was 3 days, accounting for 60.23% of the total. The duration of 10 days was the least, accounting for 12.78%. The postoperative hospital infection rate was 4.26 %. Conclusion The application of transurethral resection of anti-bacterial drugs in the hospital is more standardized and rational. The hospital infection rate is controlled at a relatively low level. However, the type of prophylaxis is relatively high and needs to be further controlled.